AISN vision

Integrating AI in Stroke Neurorehabilitation

Health services are increasingly moving towards a treatment continuum aligned with the patient journey. This transition will critically depend on the successful deployment of trustworthy AI-enhanced technologies that are accurate, secure, and trusted. The AISN project will develop and validate operating procedures and guidelines for integrating AI in a healthcare continuum, focussing on post-stroke rehabilitation.

AISN delivers a representative AI health platform built from integrating validated platforms for data acquisition and access, clinical interpretation, whole-brain simulation, clinically validated intervention delivery and optimization and model-based prediction. The AISN integrated platform will be validated in the clinical context of rehabilitation in the outpatient and at-home phase and facilitate a concrete assessment of the fundamental ways in which AI-enhanced clinical decision-support will change the care pathway and the formulation of novel AI compatible treatment guidelines. AISN ensures an ethical approach by developing legal and ethical guidelines for the robust, fair, and trustworthy deployment of AI in health and validating acceptance and transparency of its solutions. Building on the AISN platform, the project will test current standard operating procedures for integrating AI in health care and formulate and validate new ones where needed. The AISN guidelines and procedures will emphasize the evidence base and safety of clinical interventions, transparency, prognostics at varying time-scales, personalization of interventions, access to disease-specific information by clinicians, patients and their carers, and assure that the potential of AI is fully developed in the service of value-based medicine satisfying standards of security and safety. We will go beyond currently available guidelines and frameworks by emphasizing explainability, AI tools with evolving performance, and the dynamic interaction between users and algorithms.

AISN challenge

for clinical decision-support and intervention delivery

AISN Health services are increasingly moving towards a treatment continuum aligned with the patient journey from the clinic to the home environment. This transition will critically depend on the successful deployment of trustworthy AI-enhanced technologies for data processing, diagnostics, prognostics and patient-tailored intervention that are accurate, secure, and trusted by clinicians and patients alike.

The AISN platform for clinical decision-support and intervention delivery is built from the integration of three validated platforms for data acquisition and access (EBRAINS' knowledge graph), clinical interpretation, and whole-brain simulation (CHARITE's Virtual Research Environment, VirtualBrainCloud), and intervention planning, delivery and optimization (EODYNE's Rehabilitation Gaming System) with advanced AI tools for the extraction of predictive information from complex high-dimensional and heterogeneous medical data (SADDLEPOINT’s Bayesian Inference Engine). The resulting AISN platform is a representative testbed for the introduction of AI in healthcare because it both includes AI-enhanced components and modules in the cloud and the edge for data processing and interpretation, and prognostics, with clinically validated technology for automated control of interventions, personalization of treatment protocols, and patient-specific signal processing and behaviour and performance analysis.

Through the combination of machine learning and advanced data analytics and simulation, AISN shapes clinical decision-making in a patient-specific way concerning the patient's health status, prognostics of functional outcomes, and the dynamic regulation of interventions.